This is a new single courtesy of Pusha T called "Untouchable". It's got a dope Biggie sample, and dope takeover of the G.O.O.D. Music home page.
While potentially annoying, I think having to hold down your mouse on the page to hear the music is a cool way to keep the user's attention.
Update: Interestingly when it originally dropped it was using an animation from this three.js demo. It now has an animation of the single's cover art.